Cancer-miRNA Regulatory Network

Compendium of miRNA Target Genes

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B-CLL Leukemia Haslinger Cluster Number 62 (55 genes) This page contains all miRNA mediated regulation and functional enrichment for B-CLL Leukemia Haslinger cluster number 62. Information about leukemia can be found on Wikipedia, and further information about the "B-CLL Leukemia Haslinger" dataset can be found in Haslinger et al., 2004. Inferred miRNA Mediated Regulation Weeder-miRvestigator PITA TargetScan zzz999 hsa-mir-515-5p hsa-mir-548c-3p Gene Ontology Enrichment GO ID GO Term Annotated Genes in Cluster GO:0002682 regulation of immune system process 11 GO:0002684 positive regulation of immune system process 9 GO:0002756 MyD88-independent toll-like receptor signaling pathway 4 GO:0002757 immune response-activating signal transduction 6 GO:0002764 immune response-regulating signaling pathway 6 GO:0006265 DNA topological change 2 GO:0006357 regulation of transcription from RNA polymerase II promoter 12 GO:0006366 transcription from RNA polymerase II promoter 14 GO:0006464 protein modification process 20 GO:0006468 protein phosphorylation 15 GO:0006793 phosphorus metabolic process 19 GO:0006796 phosphate metabolic process 19 GO:0007243 intracellular protein kinase cascade 11 GO:0008152 metabolic process 46 GO:0009059 macromolecule biosynthetic process 27 GO:0009719 response to endogenous stimulus 10 GO:0009889 regulation of biosynthetic process 25 GO:0010468 regulation of gene expression 24 GO:0010556 regulation of macromolecule biosynthetic process 24 GO:0016310 phosphorylation 17 GO:0019222 regulation of metabolic process 30 GO:0019538 protein metabolic process 25 GO:0031323 regulation of cellular metabolic process 30 GO:0031326 regulation of cellular biosynthetic process 25 GO:0032870 cellular response to hormone stimulus 8 GO:0034130 toll-like receptor 1 signaling pathway 4 GO:0034134 toll-like receptor 2 signaling pathway 4 GO:0043170 macromolecule metabolic process 42 GO:0043412 macromolecule modification 21 GO:0044237 cellular metabolic process 44 GO:0044238 primary metabolic process 43 GO:0044260 cellular macromolecule metabolic process 40 GO:0045088 regulation of innate immune response 6 GO:0045089 positive regulation of innate immune response 5 GO:0045586 regulation of gamma-delta T cell differentiation 2 GO:0045588 positive regulation of gamma-delta T cell differentiation 2 GO:0046643 regulation of gamma-delta T cell activation 2 GO:0046645 positive regulation of gamma-delta T cell activation 2 GO:0048518 positive regulation of biological process 23 GO:0048522 positive regulation of cellular process 21 GO:0050778 positive regulation of immune response 7 GO:0050789 regulation of biological process 42 GO:0050794 regulation of cellular process 42 GO:0060255 regulation of macromolecule metabolic process 29 Overlap Between miRNA Target Genes and Enriched Gene Ontology Annotations miRNA Method GO ID GO Term Overlap GO Annotated Genes Cluster Size miRNA Targets Genes P-Value hsa-mir-548c-3p TargetScan GO:0002682 regulation of immune system process 10 11 55 44 0.0640962 hsa-mir-515-5p PITA GO:0002682 regulation of immune system process 2 11 55 9 0.2504216 hsa-mir-548c-3p TargetScan GO:0002684 positive regulation of immune system process 8 9 55 44 0.1114951 hsa-mir-515-5p PITA GO:0002684 positive regulation of immune system process 2 9 55 9 0.1543473 hsa-mir-548c-3p TargetScan GO:0002756 MyD88-independent toll-like receptor signaling pathway 4 4 55 44 0.0 hsa-mir-515-5p PITA GO:0002756 MyD88-independent toll-like receptor signaling pathway 0 4 55 9 0.5215288 hsa-mir-548c-3p TargetScan GO:0002757 immune response-activating signal transduction 6 6 55 44 0.0 hsa-mir-515-5p PITA GO:0002757 immune response-activating signal transduction 1 6 55 9 0.2513333 hsa-mir-548c-3p TargetScan GO:0002764 immune response-regulating signaling pathway 6 6 55 44 0.0 hsa-mir-515-5p PITA GO:0002764 immune response-regulating signaling pathway 1 6 55 9 0.2513333 hsa-mir-548c-3p TargetScan GO:0006265 DNA topological change 1 2 55 44 0.637037 hsa-mir-515-5p PITA GO:0006265 DNA topological change 0 2 55 9 0.3030303 hsa-mir-548c-3p TargetScan GO:0006357 regulation of transcription from RNA polymerase II promoter 10 12 55 44 0.2403608 hsa-mir-515-5p PITA GO:0006357 regulation of transcription from RNA polymerase II promoter 0 12 55 9 0.9113107 hsa-mir-548c-3p TargetScan GO:0006366 transcription from RNA polymerase II promoter 12 14 55 44 0.1575787 hsa-mir-515-5p PITA GO:0006366 transcription from RNA polymerase II promoter 0 14 55 9 0.9449007 hsa-mir-548c-3p TargetScan GO:0006464 protein modification process 16 20 55 44 0.3705286 hsa-mir-515-5p PITA GO:0006464 protein modification process 2 20 55 9 0.7139246 hsa-mir-548c-3p TargetScan GO:0006468 protein phosphorylation 12 15 55 44 0.3655369 hsa-mir-515-5p PITA GO:0006468 protein phosphorylation 2 15 55 9 0.4676991 hsa-mir-548c-3p TargetScan GO:0006793 phosphorus metabolic process 15 19 55 44 0.4249863 hsa-mir-515-5p PITA GO:0006793 phosphorus metabolic process 3 19 55 9 0.3734348 hsa-mir-548c-3p TargetScan GO:0006796 phosphate metabolic process 15 19 55 44 0.4249863 hsa-mir-515-5p PITA GO:0006796 phosphate metabolic process 3 19 55 9 0.3734348 hsa-mir-548c-3p TargetScan GO:0007243 intracellular protein kinase cascade 9 11 55 44 0.2922033 hsa-mir-515-5p PITA GO:0007243 intracellular protein kinase cascade 0 11 55 9 0.8885049 hsa-mir-548c-3p TargetScan GO:0008152 metabolic process 37 46 55 44 0.2504216 hsa-mir-515-5p PITA GO:0008152 metabolic process 7 46 55 9 0.5426067 hsa-mir-548c-3p TargetScan GO:0009059 macromolecule biosynthetic process 21 27 55 44 0.5272342 hsa-mir-515-5p PITA GO:0009059 macromolecule biosynthetic process 5 27 55 9 0.2158173 hsa-mir-548c-3p TargetScan GO:0009719 response to endogenous stimulus 7 10 55 44 0.6847252 hsa-mir-515-5p PITA GO:0009719 response to endogenous stimulus 1 10 55 9 0.5216259 hsa-mir-548c-3p TargetScan GO:0009889 regulation of biosynthetic process 19 25 55 44 0.633995 hsa-mir-515-5p PITA GO:0009889 regulation of biosynthetic process 5 25 55 9 0.1513935 hsa-mir-548c-3p TargetScan GO:0010468 regulation of gene expression 18 24 55 44 0.6846168 hsa-mir-515-5p PITA GO:0010468 regulation of gene expression 5 24 55 9 0.1242536 hsa-mir-548c-3p TargetScan GO:0010556 regulation of macromolecule biosynthetic process 18 24 55 44 0.6846168 hsa-mir-515-5p PITA GO:0010556 regulation of macromolecule biosynthetic process 5 24 55 9 0.1242536 hsa-mir-548c-3p TargetScan GO:0016310 phosphorylation 14 17 55 44 0.2625027 hsa-mir-515-5p PITA GO:0016310 phosphorylation 3 17 55 9 0.2784368 hsa-mir-548c-3p TargetScan GO:0019222 regulation of metabolic process 24 30 55 44 0.366005 hsa-mir-515-5p PITA GO:0019222 regulation of metabolic process 6 30 55 9 0.1213151 hsa-mir-548c-3p TargetScan GO:0019538 protein metabolic process 20 25 55 44 0.3703399 hsa-mir-515-5p PITA GO:0019538 protein metabolic process 4 25 55 9 0.3803862 hsa-mir-548c-3p TargetScan GO:0031323 regulation of cellular metabolic process 24 30 55 44 0.366005 hsa-mir-515-5p PITA GO:0031323 regulation of cellular metabolic process 6 30 55 9 0.1213151 hsa-mir-548c-3p TargetScan GO:0031326 regulation of cellular biosynthetic process 19 25 55 44 0.633995 hsa-mir-515-5p PITA GO:0031326 regulation of cellular biosynthetic process 5 25 55 9 0.1513935 hsa-mir-548c-3p TargetScan GO:0032870 cellular response to hormone stimulus 5 8 55 44 0.810639 hsa-mir-515-5p PITA GO:0032870 cellular response to hormone stimulus 0 8 55 9 0.7856931 hsa-mir-548c-3p TargetScan GO:0034130 toll-like receptor 1 signaling pathway 4 4 55 44 0.0 hsa-mir-515-5p PITA GO:0034130 toll-like receptor 1 signaling pathway 0 4 55 9 0.5215288 hsa-mir-548c-3p TargetScan GO:0034134 toll-like receptor 2 signaling pathway 4 4 55 44 0.0 hsa-mir-515-5p PITA GO:0034134 toll-like receptor 2 signaling pathway 0 4 55 9 0.5215288 hsa-mir-548c-3p TargetScan GO:0043170 macromolecule metabolic process 33 42 55 44 0.5136887 hsa-mir-515-5p PITA GO:0043170 macromolecule metabolic process 7 42 55 9 0.3114437 hsa-mir-548c-3p TargetScan GO:0043412 macromolecule modification 17 21 55 44 0.3192743 hsa-mir-515-5p PITA GO:0043412 macromolecule modification 3 21 55 9 0.4727963 hsa-mir-548c-3p TargetScan GO:0044237 cellular metabolic process 36 44 55 44 0.137529 hsa-mir-515-5p PITA GO:0044237 cellular metabolic process 7 44 55 9 0.4181065 hsa-mir-548c-3p TargetScan GO:0044238 primary metabolic process 34 43 55 44 0.4485841 hsa-mir-515-5p PITA GO:0044238 primary metabolic process 7 43 55 9 0.362359 hsa-mir-548c-3p TargetScan GO:0044260 cellular macromolecule metabolic process 32 40 55 44 0.3420219 hsa-mir-515-5p PITA GO:0044260 cellular macromolecule metabolic process 7 40 55 9 0.2244289 hsa-mir-548c-3p TargetScan GO:0045088 regulation of innate immune response 6 6 55 44 0.0 hsa-mir-515-5p PITA GO:0045088 regulation of innate immune response 0 6 55 9 0.6768912 hsa-mir-548c-3p TargetScan GO:0045089 positive regulation of innate immune response 5 5 55 44 0.0 hsa-mir-515-5p PITA GO:0045089 positive regulation of innate immune response 0 5 55 9 0.6059649 hsa-mir-548c-3p TargetScan GO:0045586 regulation of gamma-delta T cell differentiation 2 2 55 44 0.0 hsa-mir-515-5p PITA GO:0045586 regulation of gamma-delta T cell differentiation 0 2 55 9 0.3030303 hsa-mir-548c-3p TargetScan GO:0045588 positive regulation of gamma-delta T cell differentiation 2 2 55 44 0.0 hsa-mir-515-5p PITA GO:0045588 positive regulation of gamma-delta T cell differentiation 0 2 55 9 0.3030303 hsa-mir-548c-3p TargetScan GO:0046643 regulation of gamma-delta T cell activation 2 2 55 44 0.0 hsa-mir-515-5p PITA GO:0046643 regulation of gamma-delta T cell activation 0 2 55 9 0.3030303 hsa-mir-548c-3p TargetScan GO:0046645 positive regulation of gamma-delta T cell activation 2 2 55 44 0.0 hsa-mir-515-5p PITA GO:0046645 positive regulation of gamma-delta T cell activation 0 2 55 9 0.3030303 hsa-mir-548c-3p TargetScan GO:0048518 positive regulation of biological process 19 23 55 44 0.2284684 hsa-mir-515-5p PITA GO:0048518 positive regulation of biological process 3 23 55 9 0.5712134 hsa-mir-548c-3p TargetScan GO:0048522 positive regulation of cellular process 17 21 55 44 0.3192743 hsa-mir-515-5p PITA GO:0048522 positive regulation of cellular process 3 21 55 9 0.4727963 hsa-mir-548c-3p TargetScan GO:0050778 positive regulation of immune response 7 7 55 44 0.0 hsa-mir-515-5p PITA GO:0050778 positive regulation of immune response 1 7 55 9 0.3208121 hsa-mir-548c-3p TargetScan GO:0050789 regulation of biological process 35 42 55 44 0.07035768 hsa-mir-515-5p PITA GO:0050789 regulation of biological process 8 42 55 9 0.07012639 hsa-mir-548c-3p TargetScan GO:0050794 regulation of cellular process 35 42 55 44 0.07035768 hsa-mir-515-5p PITA GO:0050794 regulation of cellular process 8 42 55 9 0.07012639 hsa-mir-548c-3p TargetScan GO:0060255 regulation of macromolecule metabolic process 23 29 55 44 0.418736 hsa-mir-515-5p PITA GO:0060255 regulation of macromolecule metabolic process 6 29 55 9 0.09890288

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